PhD student (m/f/d) in kidney research
21.06.2024
Universitätsklinikum Erlangen AöR
Erlangen (DE)
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PhD student (m/f/d) in kidney research
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Universitätsklinikum Erlangen AöR
Erlangen (DE)
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PhD student (m/f/d) in kidney research
Universitätsklinikum Erlangen AöR
Erlangen (DE)
Aktualität: 21.06.2024
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21.06.2024, Universitätsklinikum Erlangen AöR
Erlangen (DE)
PhD student (m/f/d) in kidney research
Ihre Aufgaben:
This project is part of TRR 374 «Tubular system and interstitium of the kidney: (Patho-) physiology and crosstalk» and aims to investigate the role and interaction of uromodulin (UMOD), neutrophil extracellular traps (NET) and the complement system in inflammatory and non-inflammatory tubulointerstitial kidney disease. To this end, we will investigate the presence, abundance and interaction of these three factors and their effects on inflammatory processes, fibrosis and renal function in human kidney biopsies, animal and in vitro models. Using inhibitor and knockout strategies, we will assess whether modulation of UMOD-NET-complement interaction could represent a new therapeutic target in tubulointerstitial kidney disease.
Requirements according to TV-L
Das bringen Sie mit:
- M. Sc. in a natural science degree programme
- Highly motivated and enthusiasm for research
- Willingness to work with animals
- Experience with in vivo models (Felasa B) and/or cell culture would be advantageous
Standorte