PhD Position in Translational Cancer Immunology part time (65%) (m/w/d)

· Antigen Profiling of primary acute myeloid leukemia (AML) cells using single-cell RNA sequencing and multiparameter flow cytometry · Evaluation of novel T-cell bispecific antibody constructs for treatment of AML · Dissecting resistance mechanisms in hematologic malignancies towards bispecific antibodies and CAR-T cell therapies · Daily Research Methods: · Aseptic cell culture of cell lines and primary patient material · Isolation of peripheral blood and bone marrow mononuclear cells from patients and healthy donors · Cytotoxicity assays, co-cultures, immune cell activation and inhibition assays, proliferation analysis, and cytokine screening · Advanced flow cytometry · Presenting research findings at national and international conferences